The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2022

Filed:

Mar. 15, 2019
Applicant:

The Board of Regents of the University of Oklahoma, Norman, OK (US);

Inventors:

Adam Duerfeldt, Norman, OK (US);

Jian-xing Ma, Edmond, OK (US);

Xiaozheng Dou, Norman, OK (US);

Dinesh Nath, Meerut, IN;

Young-Hwa Shin, Oklahoma City, OK (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/52 (2006.01); C07C 69/734 (2006.01); C07D 263/32 (2006.01); C07D 277/56 (2006.01);
U.S. Cl.
CPC ...
C07D 215/52 (2013.01); C07C 69/734 (2013.01); C07D 263/32 (2013.01); C07D 277/56 (2013.01);
Abstract

Benzyl derivative compounds having peroxisome proliferator-activated receptor α (PPARα) agonistic activity, compositions containing such compounds, and methods of their use in enhancing PPARα activity for treating diseases and/or conditions involving inflammation and/or angiogenesis, particularly ocular diseases and/or conditions such as but not limited to retinal inflammation, retinal neovascularization, retinal vascular leakage, retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, and diabetic macular edema are disclosed.


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