The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
May. 19, 2020
Applicant:
AM Chemicals Llc, Oceanside, CA (US);
Inventors:
Andrei Pavel Guzaev, Escondido, CA (US);
Vladimir Y. VVedenskiy, San Diego, CA (US);
Khirud Gogoi, San Marcos, CA (US);
Assignee:
AM Chemicals LLC, Oceanside, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/22 (2006.01); C07F 9/59 (2006.01); C07F 9/6561 (2006.01); C07F 9/6558 (2006.01); C07F 9/568 (2006.01); C07F 9/24 (2006.01); C07D 205/04 (2006.01); C07D 401/12 (2006.01); C07D 409/06 (2006.01); C07D 491/18 (2006.01); C07D 493/10 (2006.01); C07D 495/04 (2006.01); C07H 1/00 (2006.01); C07H 15/26 (2006.01); C07H 21/00 (2006.01); C07J 43/00 (2006.01);
U.S. Cl.
CPC ...
C07D 211/22 (2013.01); C07D 205/04 (2013.01); C07D 401/12 (2013.01); C07D 409/06 (2013.01); C07D 491/18 (2013.01); C07D 493/10 (2013.01); C07D 495/04 (2013.01); C07F 9/2458 (2013.01); C07F 9/568 (2013.01); C07F 9/59 (2013.01); C07F 9/6561 (2013.01); C07F 9/65583 (2013.01); C07F 9/65586 (2013.01); C07H 1/00 (2013.01); C07H 15/26 (2013.01); C07H 21/00 (2013.01); C07J 43/003 (2013.01); Y02P 20/55 (2015.11);
Abstract
Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.