The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Jun. 14, 2021
Applicant:
Nutcracker Therapeutics, Inc., Emeryville, CA (US);
Inventor:
Colin James McKinlay, Emeryville, CA (US);
Assignee:
NUTCRACKER THERAPEUTICS, INC., Emeryville, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07K 7/08 (2006.01); C07K 7/06 (2006.01); A61K 9/51 (2006.01); A61K 47/54 (2017.01); A61K 31/7105 (2006.01); A61K 47/10 (2017.01); C07K 2/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0041 (2013.01); A61K 9/5123 (2013.01); A61K 9/5146 (2013.01); A61K 31/7105 (2013.01); A61K 47/10 (2013.01); A61K 47/543 (2017.08); C07K 2/00 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01);
Abstract
The present disclosure relates to lipid mixtures comprising lipidated cationic peptide compounds, such as tertiary amino lipidated and/or PEGylated cationic peptide compounds or lipitoids, for nucleic acid delivery. More specifically, the present disclosure relates to lipid nanoparticle formulations comprising lipidated cationic peptide compounds and other lipid components including structural lipid, phospholipid and shielding lipids. The present disclosure also relates to methods of preparing and using the lipid mixtures.