The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 2022
Filed:
Nov. 04, 2016
Applicant:
The Texas A&m University System, College Station, TX (US);
Inventors:
Vannakambadi K. Ganesh, Pearland, TX (US);
Magnus Hook, Houston, TX (US);
Assignee:
The Texas A&M University System, College Station, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/085 (2006.01); C07K 16/12 (2006.01); A61P 31/04 (2006.01); A61K 31/4174 (2006.01); A61K 31/43 (2006.01); A61K 31/436 (2006.01); A61K 31/496 (2006.01); A61K 31/65 (2006.01); A61K 39/40 (2006.01); A61K 45/00 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/085 (2013.01); A61K 31/4174 (2013.01); A61K 31/43 (2013.01); A61K 31/436 (2013.01); A61K 31/496 (2013.01); A61K 31/65 (2013.01); A61K 39/40 (2013.01); A61K 45/05 (2013.01); A61P 31/04 (2018.01); C07K 16/1271 (2013.01); C12N 15/00 (2013.01); C07K 2299/00 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention provides methods and compositions to reduce binding of fibrinogen to the ClfA in a gram positive bacterial infections using monoclonal antibody, a polyclonal antibody, an antigen-binding antibody fragment or a composition that specifically binds to a portion of ClfA with the sequence of SEQ ID No: 15, SEQ ID NO: 16, SEQ ID NO: 17, and SEQ ID NO: 18.