The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2022

Filed:

Apr. 25, 2019
Applicant:

Lifearc, London, GB;

Inventors:

Finn Larsen, Hawick, GB;

Carol Marion Maclean, Bathgate, GB;

Assignee:

LIFEARC, London, GB;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 5/30 (2006.01); A61K 38/09 (2006.01); A61P 5/32 (2006.01);
U.S. Cl.
CPC ...
A61K 38/09 (2013.01); A61P 5/32 (2018.01);
Abstract

The present invention relates to treating one or more estrogen related diseases while preventing or reducing the likelihood of developing estrogen deficiency related side effects, wherein the composition comprises administering a therapeutically effective amount of a Gn RH antagonist to a patient in need of the treatment, and wherein the amount of Gn RH antagonist is sufficient for providing a mean endogenous serum estradiol level of between about 20 pg/ml and 60 pg/ml, preferably between 30 pg/ml and 50 pg/m, in the patient in a treatment period of at least four weeks, without relying on 'add-back' therapy. The composition and method are simple, effective and will accordingly both increase patient acceptance and compliance of therapy.


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