The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 20, 2022

Filed:

Nov. 06, 2019
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Xinyan Cui, Wexford, PA (US);

Ian Mitchell Taylor, Pittsburgh, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/145 (2006.01); A61B 5/00 (2006.01); G01N 27/30 (2006.01); G01N 27/327 (2006.01); B82Y 30/00 (2011.01);
U.S. Cl.
CPC ...
A61B 5/14546 (2013.01); A61B 5/4064 (2013.01); G01N 27/308 (2013.01); G01N 27/3277 (2013.01); B82Y 30/00 (2013.01);
Abstract

Disclosed herein is a method of determining dopamine concentration at a target location in neural tissue. In several embodiments, the method comprises measuring current level in response to square wave voltammetry with a coated electrode of a neural probe implanted at the target location, wherein the coated electrode comprises a coating of poly 3,4 ethylene dioxythiophene (PEDOT) doped with negatively charged carbon nanotubes (CNT), and comparing the measured current level to a control current level to determine the dopamine concentration at the target location.


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