The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2022
Filed:
Jul. 08, 2020
Applicant:
Korea University Research and Business Foundation, Seoul, KR;
Inventors:
Jesang Ko, Seoul, KR;
Min-Soo Kang, Goyang-si, KR;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); A61P 1/16 (2006.01); C12N 15/113 (2010.01); G01N 33/68 (2006.01); A61K 39/02 (2006.01); C12Q 1/6883 (2018.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5023 (2013.01); A61K 39/02 (2013.01); A61P 1/16 (2018.01); C12N 15/113 (2013.01); C12Q 1/6883 (2013.01); G01N 33/6872 (2013.01); G01N 33/6893 (2013.01); A61K 48/00 (2013.01); C12N 2310/11 (2013.01); C12N 2310/122 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2320/31 (2013.01); C12Q 2600/158 (2013.01); G01N 2500/04 (2013.01); G01N 2800/085 (2013.01); G01N 2800/7085 (2013.01);
Abstract
The present invention relates to a use of leucine-zipper protein for diagnosis or treatment of fatty liver. According to the present invention, it could be confirmed that a particular fragment present at the leucine-zipper protein, especially, the N-terminal region thereof, plays an important role in the lipid metabolism in liver tissue by regulating transcriptional activity of Apolipoprotein A4, and therefore, the protein of the present invention or a fragment thereof can be utilized as a target for diagnosis, prevention, or treatment of fatty liver.