The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2022
Filed:
Sep. 07, 2018
Applicant:
Medicinal Bioconvergence Research Center, Suwon-si, KR;
Inventors:
Assignee:
MEDICINAL BIOCONVERGENCE RESEARCH CENTER, Suwon-si, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C12Q 1/02 (2006.01); C12Q 1/25 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); A61K 31/5377 (2006.01); A61K 48/00 (2006.01); A61K 31/404 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); A61K 31/404 (2013.01); A61K 31/5377 (2013.01); A61K 48/00 (2013.01); G01N 33/50 (2013.01); G01N 33/574 (2013.01); G01N 2500/02 (2013.01);
Abstract
The present invention relates to a method for screening an anticancer agent which inhibits the binding of AIMP2-DX2 and HSP70. In addition, the pharmaceutical composition for preventing or treating cancer comprising, as an active ingredient, an anticancer agent screened according to the method of the present invention inhibits the expression of HSP70 or inhibits the binding of HSP70 and AIMP2-DX2, thereby lowering the level of AIMP2-DX2 protein, and can effectively prevent the progression of cancer. As such, the pharmaceutical composition can be useful for developing a cancer treating agent.