The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2022

Filed:

Nov. 13, 2017
Applicant:

Quest Diagnostics Investments Llc, Secaucus, NJ (US);

Inventors:

Heather Sanders, San Juan Capistrano, CA (US);

Nigel J. Clarke, Vista, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); C12Q 1/6806 (2018.01); C12N 15/10 (2006.01); G01N 33/487 (2006.01); G01N 33/49 (2006.01); G01N 33/53 (2006.01); G01N 33/533 (2006.01); A61P 43/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12N 15/1058 (2013.01); C12N 15/1065 (2013.01); C12Q 1/6806 (2013.01); G01N 33/4875 (2013.01); G01N 33/49 (2013.01); G01N 33/533 (2013.01); G01N 33/5308 (2013.01); C12Q 2527/125 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/16 (2013.01);
Abstract

The present disclosure provides rapid and non-invasive methods for determining whether a patient exhibiting cancer symptoms, or at risk for hereditary cancers such as breast cancer, ovarian cancer, colon cancer, or skin cancer, will benefit from treatment with one or more therapeutic agents. These methods are based on detecting hereditary cancer-related mutations in small-volume dried biological fluid samples that are collected using a volumetric absorptive microsampling device (e.g., MITRA Tip). Kits for use in practicing the methods are also provided.


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