The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2022
Filed:
Oct. 24, 2018
Applicant:
Ariosa Diagnostics, Inc., San Jose, CA (US);
Inventors:
Assignee:
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); C12Q 1/6809 (2018.01); G16B 20/20 (2019.01); G16B 20/10 (2019.01); G16B 20/00 (2019.01); G16B 30/00 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 1/6809 (2013.01); G16B 20/10 (2019.02); G16B 20/20 (2019.02); C12Q 2600/156 (2013.01); G16B 20/00 (2019.02); G16B 30/00 (2019.02);
Abstract
The present invention provides assay systems and methods for determining the percent fetal contribution of cell-free DNA in a maternal sample from a pregnant female with an egg donor pregnancy. Further provided, are assay systems and methods for determining a statistical likelihood of the presence or absence of a fetal aneuploidy in a maternal sample using a determined percent fetal cell-free DNA in the sample.