The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2022
Filed:
Nov. 06, 2020
Applicant:
Fred Hutchinson Cancer Research Center, Seattle, WA (US);
Inventor:
Jason H. Bielas, Seattle, WA (US);
Assignee:
Fred Hutchinson Cancer Center, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6874 (2018.01); C12Q 1/6869 (2018.01); C12N 15/10 (2006.01); C40B 50/06 (2006.01); C12Q 1/6827 (2018.01); C12N 15/70 (2006.01); C12N 15/81 (2006.01); C12N 15/85 (2006.01); C40B 40/08 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12N 15/10 (2013.01); C12N 15/1065 (2013.01); C12N 15/1093 (2013.01); C12N 15/70 (2013.01); C12N 15/81 (2013.01); C12N 15/85 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6869 (2013.01); C40B 40/08 (2013.01); C40B 50/06 (2013.01);
Abstract
The present disclosure provides compositions and methods for accurately detecting mutations by uniquely tagging double stranded nucleic acid molecules with dual cyphers such that sequence data obtained from a sense strand can be linked to sequence data obtained from an anti-sense strand when sequenced, for example, by massively parallel sequencing methods.