The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2022

Filed:

Dec. 27, 2019
Applicant:

Ande Corporation, Waltham, MA (US);

Inventors:

Eugene Tan, Arlington, MA (US);

Richard F. Selden, Lincoln, MA (US);

Rosemary S. Turingan, Stoneham, MA (US);

Assignee:

ANDE CORPORATION, Waltham, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6825 (2018.01); C12Q 1/6816 (2018.01); C12N 15/10 (2006.01); G02B 27/10 (2006.01); G01N 15/14 (2006.01); B01L 7/00 (2006.01); B01L 3/00 (2006.01); C12Q 1/6818 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6825 (2013.01); B01L 3/502715 (2013.01); B01L 7/52 (2013.01); C12N 15/1017 (2013.01); C12Q 1/6816 (2013.01); C12Q 1/6818 (2013.01); B01L 3/5027 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0877 (2013.01); B01L 2300/168 (2013.01); G01N 15/1484 (2013.01); G01N 2201/06113 (2013.01); G02B 27/10 (2013.01); Y10T 436/143333 (2015.01);
Abstract

Described herein are instruments for excitation and detection of fluorophores in a plurality of functional regions in a biochip, using an excitation source and a steering element that directs a beam from the excitation source to a plurality of functional regions in the biochip, wherein the excitation source excites the fluorophores in the plurality of functional regions generating a signal that is detected such that said signal from at least one of the plurality of functional regions allows for nucleic acid quantification. Also described are systems for quantification and separation and detection using optical devices adapted for preliminary, simultaneous or sequential quantitation of nucleic acid in separate detection positions, and for the excitation and detection of multiple samples to steer both the excitation and detection beam paths to separately image each lane of a biochip.


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