The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2022

Filed:

Feb. 26, 2021
Applicant:

Sph No.1 Biochemical & Pharmaceutical Co.,ltd., Shanghai, CN;

Inventors:

Hanzhi Zhang, Shanghai, CN;

Hao Liu, Shanghai, CN;

Zhenhui Huang, Shanghai, CN;

Ning Sun, Shanghai, CN;

Wenyan Luo, Shanghai, CN;

Jinguo Ding, Shanghai, CN;

Xiaofen Liu, Shanghai, CN;

Xingchen Bian, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/62 (2006.01); C07K 1/16 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 7/62 (2013.01); C07K 1/16 (2013.01); A61K 38/00 (2013.01);
Abstract

A polymyxin B component or salts thereof, and a preparation and application thereof. The polymyxin B component includes six α,γ-diaminobutyric acids respectively at positions 1, 3-5 and 8-9, two threonine residues at positions 2 and 10, a phenylalanine residue at position 6 and a leucine residue at position 7 linked in sequence. The threonine residue at position 10 is linked to the α,γ-diaminobutyric acid at position 4 by an amido bond, and the α,γ-diaminobutyric acid at position 1 is linked to 6-methyloctyl-2-enoyl.


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