The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2022
Filed:
Mar. 14, 2019
Applicant:
Danmir Therapeutics, Llc, Haverford, PA (US);
Inventors:
Amir Pelleg, Haverford, PA (US);
Anu Mahadevan, Nestford, MA (US);
Jie Li, Winchester, MA (US);
Cynthia Morency, Andover, MA (US);
Assignee:
MERCK PATENT GMBH, Darmstadt, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/20 (2006.01); A61P 11/08 (2006.01); A61P 11/14 (2006.01); A61P 29/00 (2006.01); C07H 1/04 (2006.01); A61K 31/706 (2006.01); A61P 31/10 (2006.01);
U.S. Cl.
CPC ...
C07H 19/20 (2013.01); A61K 31/706 (2013.01); A61P 11/08 (2018.01); A61P 11/14 (2018.01); A61P 29/00 (2018.01); A61P 31/10 (2018.01); C07H 1/04 (2013.01);
Abstract
Provided are compounds compound according to Formula (I), or a pharmaceutically acceptable salt, solvate, coordination complex or prodrug thereof: wherein, Rand Rare independently selected from (C-C) alkyl. The compounds have P2X3 receptor or P2X2/3 receptor antagonist activity and are useful for the treatment of diseases and disorders characterized by activation of those receptors.