The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2022

Filed:

Apr. 10, 2018
Applicant:

Sph Xing Ling Sci. & Tech. Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Shuang Liang, Shanghai, CN;

Xiangwei Zheng, Shanghai, CN;

Qi Gao, Shanghai, CN;

Dandan Wang, Shanghai, CN;

Guoqin Zhu, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 1/08 (2006.01); C07H 17/04 (2006.01);
U.S. Cl.
CPC ...
C07H 1/08 (2013.01); C07H 17/04 (2013.01);
Abstract

The present disclosure relates to the field of pharmacology, and in particular, to a preparation method of high-purity total ginkgo flavonol glycoside. The preparation method of high-purity total ginkgo flavonol glycoside includes: (1) mixingextract powder and a first alkaline solution, subjecting to dissolution and centrifugation to obtain a supernatant; (2) subjecting the supernatant to separation with an acid-polar coupled macroporous resin column and to purification with a polyamide column, to obtain high-purity total ginkgo flavonol glycoside. The purity of the total ginkgo flavonol glycoside prepared by the preparation method of high-purity total ginkgo flavonol glycoside according to the present disclosure is ≥90%, and has good clinical application prospects; the preparation process does not require organic reagents such as petroleum ether and ethyl acetate, which is environmentally friendly; the transfer rate of the total flavonol glycoside is high.


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