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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11440922 B1

PDFFull Text
Date of Patent:
Sep. 13, 2022

Filed:

Jun. 29, 2018

Heterocyclylmethylidene derivatives and their use as modulators of mglur5 receptors

Applicant:

Recordati Industria Chimica E Farmaceutica S.p.a., Milan, IT;

Inventors:

Carlo Riva, Milan, IT;

Davide Graziani, Milan, IT;

Matteo Longhi, Milan, IT;

Elisa Callegari, Milan, IT;

Fabio Frigerio, Milan, IT;

Patrizia Angelico, Milan, IT;

Assignee:

Recordati Industria Chimica e Farmacentica S.p.A., Milan, IT;

Attorney:

Hueschen and Sage

Primary Examiner:

Charanjit Aulakh

Int. Cl.
CPC ...
C07D 211/70 (2006.01); A61K 31/445 (2006.01); C07D 498/04 (2006.01); A61P 25/28 (2006.01); C07D 207/20 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 413/12 (2006.01); C07D 471/04 (2006.01); C07D 471/08 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61P 25/28 (2018.01); C07D 207/20 (2013.01); C07D 211/70 (2013.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 413/12 (2013.01); C07D 471/04 (2013.01); C07D 471/08 (2013.01); C07D 487/04 (2013.01);
Abstract

This invention relates to compounds of formula (I) and their use as allosteric modulators of mGluR5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for the treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction, such as schizophrenia or cognitive decline, dementia or cognitive impairment, or other pathologies that can be related directly or indirectly to glutamate dysfunction.

Find Patent Forward Citations

Riva, Carlo. (2022). Heterocyclylmethylidene derivatives and their use as modulators of mglur5 receptors (U.S. Patent No. 11440922). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11440922

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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