The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2022
Filed:
Oct. 23, 2020
Applicant:
Chengdu Henghao Investment Co. Limited, Sichuan, CN;
Inventors:
Shengyong Yang, Sichuan, CN;
Linli Li, Sichuan, CN;
Assignee:
CHENGDU HENGHAO INVESTMENT CO. LIMITED, Sichuan, CN;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); C07D 279/20 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); C07D 279/20 (2013.01); C07D 471/08 (2013.01);
Abstract
10H-phenothiazine derivatives capable of inhibiting ferroptosis has structural formula (I). The derivatives, pharmaceutically acceptable salts thereof, crystal forms thereof, or solvates thereof exhibit inhibitory effect on ferroptosis, and therapeutic effect on a rat model of focal cerebral ischemia and thus can be used as a main active ingredient in the preparation of ferroptosis inhibitors. The compounds and the inhibitors prepared by the compounds have good medicinal potential and are expected to be used as drug candidates for the treatment of stroke.