The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2022

Filed:

Dec. 27, 2017
Applicant:

Minoryx Therapeutics S.l., Barcelona, ES;

Inventors:

Ana Maria García Collazo, Barcelona, ES;

Marc Martinell Pedemonte, Barcelona, ES;

Elena Cubero Jordà, Barcelona, ES;

Xavier Barril Alonso, Barcelona, ES;

Laura Pilar Rodriguez Pascau, Barcelona, ES;

Assignee:

Minoryx Therapeutics S.L., Barcelona, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 31/472 (2006.01); A61K 31/4725 (2006.01); A61K 31/5377 (2006.01); A61K 38/47 (2006.01); A61K 45/06 (2006.01); C07D 217/22 (2006.01); C07D 401/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); A61K 31/472 (2013.01); A61K 31/4725 (2013.01); A61K 31/5377 (2013.01); A61K 38/47 (2013.01); A61K 45/06 (2013.01); C07D 217/22 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 417/14 (2013.01);
Abstract

The application is directed to compounds of formula (I):(I), and formula (IA):(IA) and their salts and solvates, wherein R, R, R, R, R, n, A, A, A, and Y are as set forth in the specification, as well as to a method for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or prevention of conditions associated with the alteration of the activity of β-galactosidase, specially galactosidase beta-1 or GLB 1, including GM 1 gangliosidoses and Morquio syndrome, type B.


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