The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 13, 2022
Filed:
Mar. 25, 2020
Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);
Ruben S. Vardanyan, Tucson, AZ (US);
Victor J. Hruby, Tucson, AZ (US);
ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERISTY OF ARIZONA, Tucson, AZ (US);
Abstract
The present invention provides using a substituted 1-arylalkyl-4-acylaminopiperidine compound of Formula I: to treat various clinical conditions including, but not limited to, hemorrhagic shock, nicotine withdrawal symptoms, gastrointestinal side effects of opioids, cancer therapy, epithelial wounds, herpes zoster infection, or opioid-induced pruritus. In compound of Formula I, Ris Calkyl, Chaloalkyl, optionally substituted aryl, or optionally substituted heteroaryl; Ris Calkylene; Y is optionally substituted aryl, optionally substituted heteroaryl, or a moiety of the formula —C(═O)—X, wherein Xis —ORor —NRR, where each of R, Rand Ris H or Calkyl.