The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2022

Filed:

May. 03, 2019
Applicant:

University of Kansas, Lawrence, KS (US);

Inventors:

Wendy L. Picking, Lawrence, KS (US);

William D. Picking, Lawrence, KS (US);

Assignee:

UNIVERSITY OF KANSAS, Lawrence, KS (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/104 (2006.01); A61K 39/118 (2006.01); A61K 39/02 (2006.01);
U.S. Cl.
CPC ...
A61K 39/118 (2013.01); A61K 39/0291 (2013.01); A61K 39/099 (2013.01); A61K 39/104 (2013.01); A61K 39/107 (2013.01); C07K 2319/00 (2013.01);
Abstract

Disclosed are methods and compositions related to polypeptides comprising a fusion of the needle tip protein and translocator protein of a type III secretion apparatus (T3SA) from a type III secretion system (T3SS) of a Gram negative bacteria. Disclosed herein are fusion polypeptides comprising a fusion of a needle tip protein, such as, Bsp22, LcrV, BipD, PcrV, CT053, or CT668, or anantigenic fragment thereof; and a translocator protein, such as, BopB, YopB, BipB, PopB, CopB, or CopB2, or anantigenic fragment thereof from a Type III secretion system (T3SS) of a Gram negative bacteria, such as,, or


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