The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2022

Filed:

Feb. 06, 2014
Applicant:

The Cleveland Clinic Foundation, Cleveland, OH (US);

Inventors:

Vinod Labhasetwar, Solon, OH (US);

Hayder H. Jaffer, Rock River, OH (US);

Assignee:

The Cleveland Clinic Foundation, Cleveland, OH (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/44 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 9/51 (2006.01);
U.S. Cl.
CPC ...
A61K 38/446 (2013.01); A61K 9/0019 (2013.01); A61K 9/19 (2013.01); A61K 9/5153 (2013.01); A61K 38/44 (2013.01); C12Y 111/01006 (2013.01); C12Y 115/01001 (2013.01);
Abstract

The invention is directed to a method of treating a spinal cord injury, a neurodegenerative disease or a neuronal injury in an individual in need thereof comprising administering an effective amount of superoxide dismutase (SOD) and catalase to the individual, wherein the superoxide dismutase and the catalase are encapsulated in one or more nanoparticles that release the SOD and catalase upon administration. Another aspect of the invention is directed to compositions comprising superoxide dismutase (SOD) and catalase encapsulated in one or more nanoparticles.


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