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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11439656 B1

PDFFull Text
Date of Patent:
Sep. 13, 2022

Filed:

Aug. 30, 2019

Pharmaceutical compounds and uses thereof

Applicant:

Regents of the University of Minnesota, Minneapolis, MN (US);

Inventors:

DaQing Yang, Austin, MN (US);

Carston R. Wagner, St. Paul, MN (US);

Aniekan Okon, Boston, MA (US);

Assignee:

Regents of the University of Minnesota, Minneapolis, MN (US);

Attorney:

Schwegman Lundberg & Woessner, P.A.

Primary Examiner:

Patrick T Lewis

Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61K 31/708 (2006.01); C07H 17/02 (2006.01); A61K 31/426 (2006.01); A61K 31/365 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); A61K 31/675 (2006.01); A61K 31/196 (2006.01); A61K 31/197 (2006.01); A61K 31/175 (2006.01); A61K 31/495 (2006.01); A61K 31/366 (2006.01);
U.S. Cl.
CPC ...
A61K 31/708 (2013.01); A61K 31/175 (2013.01); A61K 31/196 (2013.01); A61K 31/197 (2013.01); A61K 31/365 (2013.01); A61K 31/366 (2013.01); A61K 31/426 (2013.01); A61K 31/495 (2013.01); A61K 31/675 (2013.01); A61K 47/6809 (2017.08); A61P 35/00 (2018.01); C07H 17/02 (2013.01);
Abstract

Described herein are small molecule cap-dependent inhibitors, including the compound of the formula: which compounds that can induce the accumulation of the p53 tumor suppressor protein in cancer cells that still express wild-type p53, as well as methods of using those compounds to, among other things, treat neuroblastoma, pediatric glioblastoma multiforme or breast cancer.

Find Patent Forward Citations

Yang, DaQing. (2022). Pharmaceutical compounds and uses thereof (U.S. Patent No. 11439656). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11439656

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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