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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11439622 B1

PDFFull Text
Date of Patent:
Sep. 13, 2022

Filed:

Nov. 30, 2016

Inhibitors of metallo-beta-lactamases

Applicant:

Oxford University Innovation Limited, Oxford, GB;

Inventors:

Jürgen Brem, Oxford, GB;

Anna M. Rydzik, Oxford, GB;

Michael A. McDonough, Oxford, GB;

Christopher J. Schofield, Oxford, GB;

Angus Morrison, Newhouse, GB;

Joanne Hewitt, Newhouse, GB;

Andrew Pannifer, Newhouse, GB;

Philip Jones, Newhouse, GB;

Assignee:

Oxford University Innovation Limited, Oxford, GB;

Attorneys:

Foley Hoag LLP

David P. Halstead

Lawrence P. Tardibono

Primary Examiner:

Kristin A Vajda

Int. Cl.
CPC ...
A61K 31/404 (2006.01); C07D 209/42 (2006.01); C07D 401/04 (2006.01); A61K 31/4439 (2006.01); A61K 45/06 (2006.01); C07D 413/10 (2006.01); A61K 31/5377 (2006.01); C07D 403/10 (2006.01); A61K 31/4155 (2006.01); A61K 31/4375 (2006.01); C07D 471/04 (2006.01); C07D 403/04 (2006.01); A61K 31/506 (2006.01); A61K 31/4196 (2006.01); A61K 31/4025 (2006.01); C07D 409/04 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); A61K 31/427 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/404 (2013.01); A61K 31/4025 (2013.01); A61K 31/4155 (2013.01); A61K 31/4196 (2013.01); A61K 31/427 (2013.01); A61K 31/4375 (2013.01); A61K 31/4439 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 31/04 (2018.01); C07D 209/42 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 403/10 (2013.01); C07D 409/04 (2013.01); C07D 413/10 (2013.01); C07D 413/14 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention relates to certain compounds, in particular, indole derivatives that function as inhibitors of bacterial metallo-beta-lactamases. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of a bacterial infection.

Find Patent Forward Citations

Brem, Jürgen. (2022). Inhibitors of metallo-beta-lactamases (U.S. Patent No. 11439622). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11439622

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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