The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 13, 2022

Filed:

Aug. 25, 2020
Applicant:

Orbus Therapeutics, Inc., Palo Alto, CA (US);

Inventors:

Victor A. Levin, Palo Alto, CA (US);

Noymi Yam, Palo Alto, CA (US);

Alexander Vakoula, Palo Alto, CA (US);

Assignee:

ORBUS THERAPEUTICS, INC., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/197 (2006.01); A61K 47/26 (2006.01); A61P 43/00 (2006.01); A61P 35/00 (2006.01); C07C 229/00 (2006.01); A61K 9/00 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/197 (2013.01); A61K 9/0053 (2013.01); A61K 9/0095 (2013.01); A61K 47/26 (2013.01); A61P 25/00 (2018.01); A61P 35/00 (2018.01); A61P 43/00 (2018.01); C07C 229/00 (2013.01);
Abstract

Eflornithine is an agent that can be used to treat glioma, especially glioma of WHO Grade II or Grade III such as anaplastic glioma. Eflornithine can suppress or prevent mutations in glioma which can cause the glioma to progress to a higher grade. The present invention describes pharmaceutical compositions that contain eflornithine or a derivative, analog, or prodrug thereof. The pharmaceutical compositions can be prepared in a number of dosage forms and may contain another therapeutically active agent or an agent that enhances the therapeutic activity of the elformithine or the derivative, analog, or prodrug thereof. The present invention also describes a kit that includes dosage forms of pharmaceutical compositions according to the present invention.


Find Patent Forward Citations

Loading…