The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2022

Filed:

Feb. 16, 2017
Applicants:

University of Miyazaki, Miyazaki, JP;

Osaka University, Osaka, JP;

Inventors:

Masamitsu Nakazato, Miyazaki, JP;

Nobuhiro Matsumoto, Miyazaki, JP;

Yasuji Arimura, Miyazaki, JP;

Hironobu Tsubouchi, Miyazaki, JP;

Toshifumi Takao, Osaka, JP;

Nobuaki Okumura, Osaka, JP;

Masafumi Fukuda, Osaka, JP;

Assignees:

UNIVERSITY OF MIYAZAKI, Miyazaki, JP;

OSAKA UNIVERSITY, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); C07K 14/705 (2006.01); C07K 14/78 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57423 (2013.01); C07K 14/705 (2013.01); C07K 14/78 (2013.01); G01N 33/6803 (2013.01);
Abstract

There is provided a simple and minimally invasive adenocarcinoma detection method. The adenocarcinoma detection method of the present invention includes a step of detecting in vitro a presence or absence of an abnormal cleavage in a specific protein in a test subject-derived sample. The abnormal cleavage in the specific protein is, for example, a cleavage resulting in one or more breaks in a peptide bond in the specific protein and/or a cleavage resulting in a deletion of one or two more amino acid residues at one or more sites of the specific protein. The adenocarcinoma detection method of the present invention includes a step of detecting a presence or amount of a protein having the abnormal cleavage or a decrease in an amount of a normal protein.


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