The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Apr. 16, 2020
The University of British Columbia, Vancouver, CA;
Carl Lars Genghis Hansen, Vancouver, CA;
Hans Zahn, Munich, DE;
Jens Huft, Marburg, DE;
Marinus Theodorus Johannes Van Loenhout, Vancouver, CA;
Kaston Leung, Vancouver, CA;
Bill Kengli Lin, Richmond, CA;
Anders Klaus, Vancouver, CA;
Samuel Alves Jana Rodrigues Aparicio, Vancouver, CA;
Sohrab Prakash Shah, Vancouver, CA;
Adi Steif, Vancouver, CA;
THE UNIVERSITY OF BRITISH COLUMBIA, Vancouver, CA;
Abstract
Methods, devices and systems for analyzing precious samples of cells, including single cells are provided. The methods, devices, and systems in various embodiments of the invention are used to assess genomic heterogeneity, which has been recognized as a central feature of many cancers and plays a critical role in disease initiation, progression, and response to treatment. The methods devices and systems are also used to analyze embryonic biopsies for preimplantation genetic diagnosis (PGD). In one embodiment, the devices, systems and methods provided herein allow for the construction of genomic and RNA-seq libraries without a pre-amplification step.