The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2022

Filed:

Feb. 10, 2022
Applicant:

Gen-probe Incorporated, San Diego, CA (US);

Inventors:

David A. Buse, San Diego, CA (US);

David Howard Combs, San Diego, CA (US);

Byron J. Knight, San Diego, CA (US);

Norbert D. Hagen, Carlsbad, CA (US);

David Opalsky, San Diego, CA (US);

Jason F. Rhubottom, Oceanside, CA (US);

Keith Moravick, Los Gatos, CA (US);

Tyler Moore, Los Gatos, CA (US);

Anita Prasad, Los Gatos, CA (US);

Bruce Richardson, Los Gatos, CA (US);

Assignee:

GEN-PROBE INCORPORATED, San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6806 (2018.01); G01N 35/04 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); B01L 3/50825 (2013.01); B01L 3/565 (2013.01); B01L 7/5255 (2013.01); C12Q 1/686 (2013.01); G01N 35/04 (2013.01); B01L 3/527 (2013.01); B01L 2200/026 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/046 (2013.01); G01N 2035/0418 (2013.01); G01N 2035/0436 (2013.01);
Abstract

A method for performing a nucleic acid amplification assay employs a thermally-conductive receptacle holder with one or more receptacle wells, each conforming to an outer surface of a lower portion of a vial. A through-hole extends from an inner surface of each well to an outer surface of the holder. A thermal element is positioned proximal to the holder for altering a temperature of the holder. A signal detection module is configured to generate an excitation signal directed through the through-hole of the well and detect an optical emission from a fluid contained in the vial supported by the well. At least one well supports a capped vial containing a reagent for a nucleic acid amplification assay and including an opaque cap sealing an open end of the vial. The lower portion of the vial is contained within a well, and the cap is situated above a top surface of the holder.


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