The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Aug. 18, 2017
Applicant:
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Inventors:
Assignee:
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 35/30 (2015.01); A61K 35/33 (2015.01); C12N 9/10 (2006.01); C12N 15/11 (2006.01); C12N 15/86 (2006.01); C12N 15/90 (2006.01); A61P 3/10 (2006.01); A61P 9/00 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 11/00 (2006.01); A61P 25/00 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); A61P 37/06 (2006.01); A61K 38/46 (2006.01); C12N 15/00 (2006.01); C12N 15/113 (2010.01); A61K 31/7088 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); A61K 35/30 (2013.01); A61K 35/33 (2013.01); C12N 9/1007 (2013.01); C12N 15/11 (2013.01); C12N 15/86 (2013.01); C12N 15/907 (2013.01); C12Y 201/01037 (2013.01); C12N 2310/20 (2017.05); C12N 2740/15031 (2013.01); C12N 2800/80 (2013.01);
Abstract
The invention relates to methods of modifying DNA methylation by contacting a catalytically inactive site specific nuclease fused to an effector domain having methylation or demethylation activity and one or more guide sequences.