The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2022

Filed:

Dec. 19, 2017
Applicant:

Sumitomo Pharma Co., Ltd., Osaka, JP;

Inventors:

Yasushi Hiramine, Kobe, JP;

Masayo Fujiwara, Kobe, JP;

Hitoshi Ban, Osaka, JP;

Futoshi Hasegawa, Nishinomiya, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/074 (2010.01); A61K 35/12 (2015.01); A61K 31/4178 (2006.01); A61K 31/422 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01); A61K 31/5365 (2006.01); A61K 31/4375 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/497 (2006.01); A61K 31/4174 (2006.01); A61K 31/4365 (2006.01); C07D 233/88 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); A61K 31/4174 (2013.01); A61K 31/4178 (2013.01); A61K 31/422 (2013.01); A61K 31/427 (2013.01); A61K 31/4365 (2013.01); A61K 31/4375 (2013.01); A61K 31/4439 (2013.01); A61K 31/4709 (2013.01); A61K 31/4725 (2013.01); A61K 31/497 (2013.01); A61K 31/5365 (2013.01); A61K 35/12 (2013.01); C07D 233/88 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01); C12N 2501/999 (2013.01);
Abstract

The present invention provides a compound of formula (1) or a salt thereof wherein ring Qis optionally-substituted Caryl, etc.; Rand Rare independently hydrogen atom, etc.; Wis Calkylene which may be optionally substituted with 1 to 3 fluorine atoms or Ccycloalkyl; Wis —NRC(O)—, etc. wherein Ris hydrogen atom or Calkyl; ring Qis optionally-substituted Caryl, etc., which has an inhibitory effect on the sphere-forming ability of cancer cells and is useful an agent for removing iPS cells.


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