The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Apr. 12, 2019
Asana Biosciences, Llc, Lawrenceville, NJ (US);
Roger A. Smith, Chester Springs, PA (US);
Nitin K. Damle, Berwyn, PA (US);
Aleksandr V. Yurkovetskiy, Littleton, MA (US);
Mao Yin, Needham, MA (US);
Timothy B. Lowinger, Carlisle, MA (US);
Joshua D. Thomas, Natick, MA (US);
Cheri A. Stevenson, Haverhill, MA (US);
Venu R. Gurijala, Lancaster, MA (US);
Asana BioSciences, LLC, Lawrenceville, NJ (US);
Abstract
A polymeric scaffold useful for conjugating with a protein based recognition-molecule (PBRM) to form a PBRM-polymer-drug conjugate is described herein. The scaffold includes one or more terminal maleimido groups. Also disclosed is a PBRM-polymer-drug conjugate prepared from the scaffold. Compositions comprising the conjugates, methods of their preparation, and methods of treating various disorders with the conjugates or their compositions are also described.