The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Nov. 26, 2018
Dart Neuroscience, Llc, Dallas, TX (US);
Brett Bookser, San Diego, CA (US);
Iriny Botrous, San Diego, CA (US);
Aaron Burns, San Diego, CA (US);
DeMichael Chung, San Diego, CA (US);
Brian Dyck, San Diego, CA (US);
Andrew Kleinke, San Diego, CA (US);
Dange Vijay Kumar, San Diego, CA (US);
Margaret McCarrick, San Diego, CA (US);
Nicholas Raffaele, San Diego, CA (US);
Joe Tran, San Marcos, CA (US);
Michael Weinhouse, Lanai City, HI (US);
Dart Neuroscience LLC, Dallas, TX (US);
Abstract
Substituted furanopyrimidine chemical entities of Formula (I): wherein Rhas any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive therapies; modulating and treating disorders mediated by PDE1 activity or dopaminergic signaling; treating neurological disorders, CNS disorders, dementia, neurodegenerative diseases, and trauma-dependent losses of function; treating stroke, including cognitive and motor deficits during stroke rehabilitation; facilitating neuroprotection and neurorecovery; enhancing the efficiency of cognitive and motor training, including animal skill training protocols; and treating peripheral disorders, including cardiovascular, renal, hematological, gastroenterological, liver, cancer, fertility, and metabolic disorders.