The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2022

Filed:

Nov. 30, 2018
Applicant:

Bial-portela & Cª, S.a., S. Mamede Do Coronado, PT;

Inventors:

Laszlo Erno Kiss, São Mamede Do Coronado, PT;

Alexander Beliaev, São Mamede Do Coronado, PT;

Tino Rossi, São Mamede Do Coronado, PT;

Pedro Nuno Leal Palma, São Mamede Do Coronado, PT;

Patrício Manuel Vieira Araujo Soares Da Silva, São Mamede Do Coronado, PT;

Rui Pinto, São Mamede Do Coronado, PT;

Francisco Cardona, São Mamede Do Coronado, PT;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 519/00 (2006.01); A61P 19/10 (2006.01); A61P 9/04 (2006.01); A61P 9/12 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 9/04 (2018.01); A61P 9/12 (2018.01); A61P 19/10 (2018.01); C07D 519/00 (2013.01); C07B 2200/05 (2013.01);
Abstract

This invention relates to: (a) compounds of formula Ia (with R1, R4 to R6, n and A as defined herein) and pharmaceutically acceptable salts or solvates thereof that are useful as dopamine-β-hydroxylase inhibitors; (b) pharmaceutical compositions (comprising such compounds, salts or solvates; (c) the use of such compounds, salts or solvates in therapy; (d) therapeutic methods of treatment using such compounds, salts or solvates; and (e) processes and intermediates useful for the synthesis of such compounds.


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