The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Mar. 23, 2020
Nippon Chemiphar Co., Ltd, Tokyo, JP;
Masatoshi Ushioda, Tokyo, JP;
Kunio Kobayashi, Saitama, JP;
Daisuke Saito, Tokyo, JP;
Shogo Sakuma, Saitama, JP;
Toshiyasu Imai, Tokyo, JP;
Kazuhide Inoue, Fukuoka, JP;
NIPPON CHEMIPHAR CO., LTD, Tokyo, JP;
Abstract
The present invention relates to a diazepine derivative represented by the following general formula (I) (in the formula, Rand Rrepresent hydrogen atom and the like, or Rand Rbind together to form a naphthalene ring and the like together with the benzene ring to which they bind, Rand Rrepresent hydrogen atom and the like, Rrepresents hydrogen atom and the like, Rand Rrepresent hydrogen atom and the like, X represents C, CH or N, Y represents N, NH or C(═O), provided that when X is N, Y is not N or NH, and when X is C or CH, Y is not C(═O), Z represents oxygen atom or sulfur atom, A represents benzene ring and the like, B represents NHC(═O) and the like, D represents an atomic bond and the like, E represents an atomic bond and the like, G represents benzene which may be substituted and the like, and m represents an integer of 0 to 5) or a pharmacologically acceptable salt thereof, and a P2X4 receptor antagonist.