The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2022

Filed:

Aug. 19, 2020
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Neil Vasdev, Cambridge, MA (US);

Huan Steven Liang, Cambridge, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 215/28 (2006.01); C07D 401/12 (2006.01); A61P 35/00 (2006.01); A61K 51/04 (2006.01); C07D 215/26 (2006.01); A61K 45/06 (2006.01); A61P 25/28 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 215/28 (2013.01); A61K 45/06 (2013.01); A61K 51/0455 (2013.01); A61P 25/28 (2018.01); A61P 35/00 (2018.01); C07B 59/002 (2013.01); C07D 215/26 (2013.01); C07D 401/12 (2013.01); A61K 2123/00 (2013.01);
Abstract

The present application provides compounds useful in methods of treating neurological disorders such as Alzheimer's disease, and cancer such as prostate cancer. Also provided herein are radiolabeled compounds useful for imaging techniques, and techniques for diagnosis and monitoring of treatment of neurological disorders and cancer. An exemplary radiolabeled compound provided herein is useful as a radiotracer for positron emission tomography or single-photon emission computed tomography. Methods for preparing radiolabeled compounds and methods for preparing unlabeled compounds are also provided.


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