The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Mar. 22, 2021
Applicant:
Resilio Therapeutics, Llc, Durham, NC (US);
Inventors:
Francis Xavier Tavares, Durham, NC (US);
Michael Peter Vitek, Efland, NC (US);
Assignee:
Resilio Therapeutics, LLC, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 229/26 (2006.01); C07D 317/38 (2006.01); A61P 25/28 (2006.01); A61P 25/00 (2006.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07C 229/26 (2013.01); A61K 45/06 (2013.01); A61P 25/00 (2018.01); A61P 25/28 (2018.01); A61P 35/00 (2018.01); C07D 317/38 (2013.01);
Abstract
Novel compounds of formula (II) are disclosed. Compounds of formula (II) comprise ornithine derivatives or compounds that can metabolize under physiological conditions to ornithine. The pH and plasma stability of compounds of formula (II) is also described. Also disclosed are methods for the treatment of neurodegenerative diseases such as Alzheimer's Disease using compounds of formula (II).