The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2022

Filed:

Jul. 20, 2018
Applicant:

University of Florida Research Foundation, Inc., Gainesville, FL (US);

Inventor:

Stanislav Igorevich Svetlov, Gainesville, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 217/28 (2006.01); A61K 31/133 (2006.01);
U.S. Cl.
CPC ...
C07C 217/28 (2013.01); A61K 31/133 (2013.01);
Abstract

Compounds, pharmaceutical compositions, and methods for treating cancer, in particular brain cancer, are provided, including amphiphilic fatty acid/alcohol ethers (AIPs) comprising endocannabinoid and FABP motifs covalently linked to a beta-adrenoreceptor antagonist motif in one molecule. The invention includes methods for inhibiting growth of brain cancer cells by contacting the compound(s) with brain cancer cells. The invention provides a method for treating both brain cancer and brain cancer metastases, and for suppression of regrowth of brain cancer cells after radiation, surgical treatment, or chemotherapy of brain cancer. The invention also comprises an optimized chemical synthesis of the AIP compounds and methods of using the compounds, alone or in combination with another agent, for suppressing the growth of brain cancer cells, and enhancing survival of normal CNS cells, or improving recuperation from radiation, surgical or chemotherapy.


Find Patent Forward Citations

Svetlov, Stanislav. (2022). Compositions and methods for treatment of central nervous system tumors (U.S. Patent No. 11434195). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11434195

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