logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11433320 B1

PDFFull Text
Date of Patent:
Sep. 06, 2022

Filed:

Jan. 28, 2019

Difluoroacetic acid ion pairing reagent for high sensitivity, high resolution lc-ms of biomolecules

Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Matthew A. Lauber, North Smithfield, RI (US);

Jennifer M. Nguyen, Uxbridge, MA (US);

Ximo Zhang, Framingham, MA (US);

Nilini Ranbaduge, Hopkinton, MA (US);

Robert Birdsall, Southborough, MA (US);

Henry Shion, Hopkinton, MA (US);

Assignee:

Waters Technologies Corporation, Milford, MA (US);

Attorneys:

Womble Bond Dickinson (US) LLP

Deborah M. Vernon

Primary Examiner:

Ryan B Huang

Int. Cl.
CPC ...
B01D 15/42 (2006.01); B01D 15/32 (2006.01); G01N 30/34 (2006.01); B01D 15/16 (2006.01); B01J 20/283 (2006.01); B01J 20/287 (2006.01); G01N 30/72 (2006.01); G01N 30/84 (2006.01); B01D 15/30 (2006.01);
U.S. Cl.
CPC ...
B01D 15/426 (2013.01); B01D 15/166 (2013.01); B01D 15/325 (2013.01); B01D 15/327 (2013.01); B01J 20/283 (2013.01); B01J 20/287 (2013.01); G01N 30/34 (2013.01); G01N 30/7266 (2013.01); G01N 30/84 (2013.01); B01D 15/305 (2013.01); G01N 30/7233 (2013.01); G01N 2030/8452 (2013.01);
Abstract

The present disclosure relates to the determination of analytes in a sample using chromatography. The present disclosure provides methods of separating an analyte from a sample. A mobile phase is flowed through a chromatography column. The mobile phase includes about 0.005% (v/v) to about 0.20% (v/v) difluoroacetic acid and less than about 100 ppb of any individual metal impurity. A sample including the analyte is injected into the mobile phase. The analyte is separated from the sample.

Find Patent Forward Citations

Lauber, Matthew. (2022). Difluoroacetic acid ion pairing reagent for high sensitivity, high resolution lc-ms of biomolecules (U.S. Patent No. 11433320). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11433320

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…