The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2022

Filed:

Mar. 08, 2019
Applicant:

Corflow Therapeutics Ag, Baar, CH;

Inventors:

Robert S. Schwartz, Inver Grover Heights, MN (US);

Jon Helge Hoem, Oberaegeri, CH;

Martin T. Rothman, Santa Rosa, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61M 5/172 (2006.01); A61M 5/142 (2006.01); A61M 25/10 (2013.01); A61M 25/00 (2006.01); A61B 17/22 (2006.01); A61B 5/00 (2006.01); A61M 25/09 (2006.01); A61M 5/168 (2006.01);
U.S. Cl.
CPC ...
A61M 5/1723 (2013.01); A61B 5/6853 (2013.01); A61B 17/22 (2013.01); A61M 5/142 (2013.01); A61M 25/007 (2013.01); A61M 25/0069 (2013.01); A61M 25/10 (2013.01); A61B 2017/22051 (2013.01); A61B 2017/22084 (2013.01); A61M 5/16827 (2013.01); A61M 2005/1726 (2013.01); A61M 2025/0002 (2013.01); A61M 2025/09175 (2013.01); A61M 2205/3334 (2013.01); A61M 2230/30 (2013.01);
Abstract

Devices for the diagnosis and treatment of microvascular obstruction (MVO) and other dysfunctional diseases of the microvasculature of many organs, including the heart. The present subject matter provides novel devices and methods to detect and measure or treat MVO in real time during scenarios such as invasive angiographic/therapeutic procedures. Such procedures include therapy for organ systems including the heart (acute myocardial infarction-primary percutaneous coronary intervention (PPCI)), brain stroke (CVA), bowel ischemia/infarction, pulmonary emboli/infarction, critical limb ischemia/infarction, renal ischemia/infarction, and others. Using methods of the invention, a system comprising specialized infusion and sensing catheter, diagnostic agents, therapeutic agents, and control console with specialized algorithms can both diagnose and treat MVO by eliminating the microvascular clot and debris causing the obstruction. The techniques involve a combination of novel devices, methods, and software to simultaneously diagnose and treat MVO.


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