The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Dec. 16, 2016
The General Hospital Corporation, Boston, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Xtuit Pharmaceuticals, Inc., Waltham, MA (US);
Peter Blume-Jensen, Newton, MA (US);
Donald E. Chickering, III, Framingham, MA (US);
Paul W. Kopesky, Lexington, MA (US);
Lawrence A. Reiter, Mystic, CT (US);
Alan Crane, Newton, MA (US);
Robert S. Langer, Newton, MA (US);
Rong Tong, Cambridge, MA (US);
Rakesh K. Jain, Wellesley, MA (US);
Vikash Pal Singh Chauhan, Boston, MA (US);
Joao Incio, Boston, MA (US);
Dai Fukumura, Newton, MA (US);
The General Hospital Corporation, Boston, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
XTUIT Pharmaceuticals, Inc., Waltham, MA (US);
Abstract
Provided herein are polymers, pH-sensitive polymers and/or linkers; conjugates comprising said polymers and/or linkers, optionally, coupled to one or more agents and/or targeting moieties; and particles (e.g., nanoparticles comprising the aforesaid polymers, linkers and/or conjugates), which can be used to enhance the delivery and/or efficacy of one or more agents in a subject.