The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2022

Filed:

Mar. 28, 2017
Applicants:

Minjie HU, Foster City, CA (US);

Yu LI, Johns Creek, GA (US);

Xiaoling Liu, Pearland, TX (US);

Rebecca HU, Foster City, CA (US);

Inventors:

Minjie Hu, Foster City, CA (US);

Yu Li, Johns Creek, GA (US);

Xiaoling Liu, Pearland, TX (US);

Rebecca Hu, Foster City, CA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/768 (2015.01); A61K 39/39 (2006.01); A61K 35/745 (2015.01); A61P 35/00 (2006.01); A61K 35/741 (2015.01); A61K 45/06 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 35/741 (2013.01); A61K 35/745 (2013.01); A61K 39/39 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12N 7/00 (2013.01); A61K 2039/55594 (2013.01); C12N 2710/24021 (2013.01); C12N 2710/24032 (2013.01); C12N 2710/24121 (2013.01); C12N 2710/24132 (2013.01);
Abstract

Therapeutic methods for administering gut microbiota and oncolytic viruses to a subject are provided. The gut microbiota serve to pre-condition, the subject's immune system to antitumor responses and augments anticancer activity of the oncolytic vims. Combinations of the gut. microbiota and viruses and uses thereof for treating and preventing cancer are provided. The present disclosure also provides methods for building elite responder selection platforms through hierarchical clustering analysis of genomic profiles for human gut microbiome.


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