The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 2022
Filed:
Jun. 10, 2021
Applicant:
Hikma Pharmaceuticals Usa Inc., Berkeley Heights, NJ (US);
Inventors:
Mahmoud Ghannam, Amman, JO;
Shahin Fesharaki, Weston, FL (US);
Mohammad Al Hreebat, Amman, JO;
Ahmad Arif Mohammad, Amman, JO;
Assignee:
HIKMA PHARMACEUTICALS USA, INC., Berkeley Heights, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 9/48 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 9/0053 (2013.01); A61K 9/4858 (2013.01); A61K 9/4866 (2013.01);
Abstract
Stable and bioavailable oral dosage forms of ibrutinib, the dosage forms comprising ibrutinib and an acidifying agent. The dosage forms can further comprise a binder, such as sodium alginate, a surfactant, a lubricant, a filler and/or a disintegrant. Methods of treating cancers, particularly blood cancers, and graft versus host disease comprising administering to a patient in need thereof a dosage form comprising ibrutinib and an acidifying agent.