The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 2022

Filed:

Aug. 17, 2018
Applicant:

Vyne Pharmaceuticals Ltd., Rehovot, IL;

Inventors:

Dov Tamarkin, Macabim, IL;

Helena Shifrin, Rehovot, IL;

Rita Keynan, Rehovot, IL;

Enbal Ziv, Gedera, IL;

Tal Berman, Rishon le Ziyyon, IL;

David Schuz, Gimzu, IL;

Elana Gazal, Rehovot, IL;

Assignee:

Vyne Therapeutics Inc., Bridgewater, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/12 (2006.01); A61K 45/06 (2006.01); A61K 31/20 (2006.01); A61K 31/355 (2006.01); A61K 47/06 (2006.01); A61K 31/59 (2006.01); A61K 9/00 (2006.01); A61K 31/65 (2006.01); A61K 47/14 (2017.01); A61K 47/24 (2006.01); A61K 8/04 (2006.01); A61K 31/522 (2006.01); A61K 31/7056 (2006.01); A61K 47/34 (2017.01); A61K 47/44 (2017.01);
U.S. Cl.
CPC ...
A61K 9/12 (2013.01); A61K 8/046 (2013.01); A61K 9/0014 (2013.01); A61K 9/122 (2013.01); A61K 31/20 (2013.01); A61K 31/355 (2013.01); A61K 31/522 (2013.01); A61K 31/59 (2013.01); A61K 31/65 (2013.01); A61K 31/7056 (2013.01); A61K 45/06 (2013.01); A61K 47/06 (2013.01); A61K 47/14 (2013.01); A61K 47/24 (2013.01); A61K 47/34 (2013.01); A61K 47/44 (2013.01); Y10S 514/871 (2013.01); Y10S 514/945 (2013.01);
Abstract

A waterless foamable pharmaceutical composition suitable for external administration is disclosed. The composition includes a foamable carrier least one liquefied or compressed gas propellant. The foamable carrier includes at least one liquid oil; at least one silicone and at least one least one stabilizing agent; wherein the stabilizing agent selected from the group consisting of about 0.01% to about 25% by weight of at least one surface-active agent alone or on combination with a foam adjuvant; and about 0% to about 5% by weight of at least one polymeric agent alone or on combination with a foam adjuvant; and mixtures thereof. Pharmaceutical compositions comprising active agents, methods for their preparation, propellants suitable for use with the carriers and uses thereof are further described.


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