The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2022

Filed:

Aug. 06, 2018
Applicant:

Billiontoone, Inc., Palo Alto, CA (US);

Inventors:

David Tsao, Palo Alto, CA (US);

Oguzhan Atay, Palo Alto, CA (US);

Assignee:

BillionToOne, Inc., Menlo Park, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/34 (2006.01); G16B 40/00 (2019.01); C12Q 1/6869 (2018.01); C12Q 1/6851 (2018.01); C12Q 1/6883 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
G16B 40/00 (2019.02); C12Q 1/6851 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01);
Abstract

Embodiments of a method and/or system can include generating a set of target-associated molecules (e.g., spike-in molecules) associated with one or more biological targets; generating one or more spike-in mixtures based on processing the set of target-associated molecules with one or more samples including the one or more biological targets; performing one or more Sanger sequencing operations on the one or more spike-in mixtures; determining one or more abundance metrics based on chromatogram-related outputs from the one or more Sanger sequencing operations; and/or facilitating characterization of one or more medical conditions based on the one or more abundance metrics.


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