The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Aug. 25, 2017
The Broad Institute, Inc., Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
The Regents of the University of California, Oakland, CA (US);
Aviv Regev, Cambridge, MA (US);
Vijay K. Kuchroo, Boston, MA (US);
Jellert Gaublomme, Cambridge, MA (US);
Youjin Lee, Boston, MA (US);
Chao Wang, Boston, MA (US);
Nir Yosef, Oakland, CA (US);
Hongkun Park, Cambridge, MA (US);
James Kaminski, Oakland, CA (US);
The Broad Institute, Inc., Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
This invention relates generally to compositions and methods for identifying the regulatory network that modulates, controls or otherwise influences T cell balance, for example, Th17 cell differentiation, maintenance and/or function, as well compositions and methods for exploiting the regulatory network that modulates, controls or otherwise influences T cell balance in a variety of therapeutic and/or diagnostic indications. This invention also relates generally to identifying and exploiting target genes and/or target gene products that modulate, control or otherwise influence T cell balance in a variety of therapeutic and/or diagnostic indications.