The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Oct. 22, 2019
Applicant:
Gradientech Ab, Uppsala, SE;
Inventors:
Assignee:
GRADIENTECH AB, Uppsala, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/18 (2006.01); C12M 1/16 (2006.01); C12Q 1/02 (2006.01); C12M 3/06 (2006.01); C12M 1/12 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); C12M 1/16 (2013.01); C12M 21/00 (2013.01); C12M 23/16 (2013.01); C12M 25/14 (2013.01); C12M 41/46 (2013.01); C12Q 1/02 (2013.01); B01L 3/5027 (2013.01);
Abstract
A fluidic device has a culture chamber configured to house a 3D culture matrix comprising a culture of microorganisms. A concentration gradient of a test substance is established over the 3D culture matrix by providing respective fluid flows at different end portions of the culture chamber and comprising different concentrations of the test substance. The response of the microorganisms to the test substance is determined based on the position of a border zone in the 3D culture matrix.