The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Jun. 26, 2015
Applicant:
Nogra Pharma Limited, Dublin, IE;
Inventors:
Assignee:
Nogra Pharma Limited, Dublin, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 495/04 (2006.01); C07C 233/29 (2006.01); C07C 233/73 (2006.01); C07C 235/38 (2006.01); C07C 235/46 (2006.01); C07D 209/08 (2006.01); C07D 209/14 (2006.01); C07D 209/86 (2006.01); C07D 209/94 (2006.01); C07D 213/75 (2006.01); C07D 235/30 (2006.01); C07D 277/64 (2006.01); C07D 277/82 (2006.01); C07D 333/36 (2006.01);
U.S. Cl.
CPC ...
C07D 495/14 (2013.01); C07C 233/29 (2013.01); C07C 233/73 (2013.01); C07C 235/38 (2013.01); C07C 235/46 (2013.01); C07D 209/08 (2013.01); C07D 209/14 (2013.01); C07D 209/86 (2013.01); C07D 209/94 (2013.01); C07D 213/75 (2013.01); C07D 235/30 (2013.01); C07D 277/64 (2013.01); C07D 277/82 (2013.01); C07D 333/36 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 495/04 (2013.01);
Abstract
The present invention is generally directed towards compounds capable of binding the aryl hydrocarbon receptor and modulating its activity, methods of treating inflammatory conditions such as Crohn's disease using such compounds, and pharmaceutical compositions comprising such compounds. Also provided are methods of increasing levels of IL-22 in a subject and/or decreasing levels of IFN-γ in a subject.