The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Sep. 13, 2019
Applicant:
Aerie Pharmaceuticals, Inc., Bedminster, NJ (US);
Inventors:
Mitchell A. deLong, Chapel Hill, NC (US);
Jill M. Sturdivant, Chapel Hill, NC (US);
Cynthia L. Lichorowic, Raleigh, NC (US);
Andriy Kornilov, Ypsilanti, MI (US);
Assignee:
Aerie Pharmaceuticals, Inc., Bedminster, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 417/12 (2006.01); C07D 401/12 (2006.01); A61P 27/06 (2006.01); C07D 413/12 (2006.01); C07D 405/12 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61P 27/06 (2018.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract
Provided herein are amino isoquinolinyl amide and sulfonamide compounds that affect the function of kinases and other proteins in a cell and that are useful as therapeutic agents. In particular, these compounds are useful in the treatment of eye diseases such as glaucoma and retinal diseases, as anti-inflammatory agents, for the treatment of cardiovascular diseases, and for diseases characterized by abnormal growth, such as cancers.