The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 30, 2022

Filed:

Jan. 18, 2017
Applicant:

Biogen MA Inc., Cambridge, MA (US);

Inventors:

Timothy Chan, Cambridge, MA (US);

Kevin M. Guckian, Cambridge, MA (US);

Tracy Jenkins, Cambridge, MA (US);

Jermaine Thomas, Cambridge, MA (US);

Jeffrey Vessels, Cambridge, MA (US);

Gnanasambandam Kumaravel, Cambridge, MA (US);

Robert Meissner, Cambridge, MA (US);

Joseph P. Lyssikatos, Cambridge, MA (US);

Brian Lucas, Cambridge, MA (US);

Irina Leaf, Cambridge, MA (US);

Jeremy Duffield, Cambridge, MA (US);

Nathan Genung, Cambridge, MA (US);

Assignee:

BIOGEN MA INC., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 45/06 (2013.01);
Abstract

Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, and methods for their use and production. Formula (I) The compounds are IRAK-4 inhibitors useful for treating an inflammatory disease, an autoimmune disease, cancer, a cardiovascular disease, a disease of the central nervous system, a disease of the skin, an ophthalmic disease and condition, and a bone disease.


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