The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Nov. 09, 2018
Applicant:
Hepagene Therapeutics (Hk) Limited, Wan Chai, HK;
Inventor:
Xiaodong Xu, Doylestown, PA (US);
Assignee:
Hepagene Therapeutics (HK) Limited, Wan Chai, HK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); A61P 1/16 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 451/02 (2006.01); C07D 491/08 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61P 1/16 (2018.01); C07D 401/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 451/02 (2013.01); C07D 491/08 (2013.01);
Abstract
The present technology is directed to compounds, compositions, and methods related to inhibition of ASK1. In particular, the present compounds (e.g., compounds of Formula I as defined herein) and compositions may be used to treat ASK1-mediated disorders and conditions, including, e.g., fibrotic diseases and acute and chronic liver diseases, among others.