The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Aug. 02, 2018
Bayer Aktiengesellschaft, Leverkusen, DE;
Bayer Pharma Aktiengesellschaft, Berlin, DE;
The Broad Institute, Inc., Cambridge, MA (US);
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Manuel Ellermann, Berlin, DE;
Stefan Nikolaus Gradl, Berlin, DE;
Charlotte Christine Kopitz, Falkensee, DE;
Martin Lange, Berlin, DE;
Adrian Tersteegen, Wuppertal, DE;
Philip Lienau, Berlin, DE;
Christa Hegele-Hartung, Mülheim an der Ruhr, DE;
Detlev Sülzle, Berlin, DE;
Timothy A. Lewis, Cambridge, MA (US);
Heidi Greulich, Cambridge, MA (US);
Xiaoyun Wu, Cambridge, MA (US);
Matthew Meyerson, Boston, MA (US);
Alex Burgin, Cambridge, MA (US);
Bayer Aktiengesellschaft, Leverkusen, DE;
Bayer Pharma Aktiengesellschaft, Berlin, DE;
The Broad Institute, Inc., Cambridge, MA (US);
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Abstract
The present invention provides dihydrooxydiazinone compounds of general formula (I): in which R, R, R, and R, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.